Hope is a complex and multifaceted syndrome, an emotion as well as a virtue. It requires attention in a Christian economic paradigm oriented at justice and human flourishing. This article makes a case for this type of interdisciplinary research. Our focus lies on hope with a high (aspirational) agency and prudence. In recent economics, with increasing appreciation for relationships, well-being, and the common good, there is an openness to motivational concepts such as hope. Positive psychology has also given attention to hope as a form of well-being and resilience. We stress the importance of embedding hope in a Christian worldview in the tradition of Abraham Kuyper’s Pro Rege and the work of Nicholas Wolterstorff. Christian thinking fosters the relationship between hope, faith, moral orientation, and worship as imagining a different future. Hope as a prudent art of potentiality is a transformational power, creating a society where humans can flourish and fight off anxiety and despair.